Hi there.
it is advised you do not use Hi-Toro for P-UAE i believe, but instead create configs from scratch with the minimum number of options set. The linux version has a GUI i think, and maybe the OSX version a limited GUI? It may depend on the build options.
What build of P-UAE are you using? There have been many updates by gnostic, to such an extent that I have not been able to keep up with the changes myself.
http://eab.abime.net/showthread.php?t=620542.4.0 appears to be the last version, but i have yet to see a build for OSX.
There should be benefits to using P-UAE for games, such as fixes to joystick/joypad code etc which have bugs in the last version of e-uae.... whether you notice these however depends on how you are using it i guess though.
I've only ever had success really using it as an a500 emulator, and limited at that - sadly I dont have time to play-around with it like i used to.